Research assistant job at KINGS COLLEGE LONDON

job description

We are looking for a highly motivated and enthusiastic Research Assistant to join the dynamic Autoimmunity and Immune Regulation Research Team at King’s College London. As part of the Department of Immunobiology, the group focuses on the analysis of immune responses in a range of human autoimmune and inflammatory diseases with a particular interest in type 1 diabetes. Key and frequent interactions between clinicians , collaborators and basic scientists are central to our research approach and our goals include the advancement of basic science and its application to the clinic.

The successful candidate will be involved in performing state-of-the-art immune assays investigating the effect of neuromodulation on the adaptive immune system with a primary focus on effector and regulatory T cell responses.

The successful candidate will be comfortable working in a multidisciplinary, collaborative and fast-paced research environment. They will be able to work independently but will also have excellent interpersonal skills to work in a team. Experience with relevant laboratory techniques including immune cell isolation and culture and flow cytometry would be an advantage, however, enthusiasm, dedication and a strong desire to learn new skills will be more value and relevant training and advice will be provided by our experienced team. of scientists.

This position will be offered on a 12-month fixed-term contract

This is a full time position

Main responsibilities

• Process and analyze samples from human subjects and animal models.

• Perform a range of immunological tests to quantify and profile pathogenic and regulatory immune responses.

• Perform tissue culture, including isolation and purification of cells from human blood samples.

• Perform in vitro assays to measure immune function including high end flow cytometry, ELISPOT/FLUROSPOT, suppression assays, proliferation assays and a range of molecular assays (RT-PCR, RNA-Seq) .

• The candidate will be responsible for analyzing and reporting analytical results.

• The incumbent will be required to perform work in accordance with GCLP guidelines

The above list of responsibilities may not be exhaustive and the post holder will be required to undertake the duties and responsibilities reasonably expected within the scope and classification of the position.

Skills, knowledge and experience

Essential criteria

1. A BSc in a relevant field

2. A good knowledge of the human immune system

3. Laboratory research experience in a biomedical context

4. Ability to learn new techniques

5. Effective time management and organizational skills

6. Honest and Accurate Data Recording

Desirable criteria

1. A master’s degree in a relevant field (covering basic immunology)

2. Experience in handling clinical trial samples in accordance with GCLP guidelines.

3. Tissue culture experiment

4. Experience in setting up tests to measure immune cell function.

5. High-Dimensional Flow Cytometry Experiment

6. Experience in Isolation and Enrichment of Immune Cell Subsets

7. Knowledge of computer programming (e.g. R or Python)

More information

The successful candidate should be comfortable working in a fast-paced, collaborative, multidisciplinary research environment.

An important part of this position is the ability to work independently and as part of a dynamic, matrix team environment.

The candidate will maintain good experimental record keeping and have excellent writing and communication skills.

The appointee will possess problem-solving skills to help achieve the goal and the ability to prioritize with the project team.

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